Editorial Expression of Concern: SWI/SNF-mutant cancers depend on catalytic and non
Addendum to: Nature Medicine https://doi.org/10.1038/nm.3968, published online 9 November 2015.
The Editors would like to alert the readers that concerns have been raised regarding some of the data presented in this article, specifically:
-
In Fig. 2d and f, the H3K27me3 blots appear highly similar (with different exposure)
-
In Supplementary Fig. 2a, A549 well 6 and TOV21G well 4 appear highly similar
-
In Supplementary Fig. 4g, RCC4 and H1299 plates (all wells) appear highly similar
The original data are no longer available due to the age of the article. Readers are therefore advised to interpret these data with caution.
Kimberly H. Kim, Woojin Kim, Thomas P. Howard, Francisca Vazquez, Aviad Tsherniak, Weishan Wang, Jeffrey R. Haswell, Loren D. Walensky, William C. Hahn, Stuart H. Orkin & Charles W. M. Roberts agree with this Editorial Expression of Concern. Jennifer N. Wu could not be reached by email.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kim, K.H., Kim, W., Howard, T.P. et al. Editorial Expression of Concern: SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2. Nat Med (2026). https://doi.org/10.1038/s41591-026-04708-9
Published:
Version of record:
DOI: https://doi.org/10.1038/s41591-026-04708-9
How it works
Once you click Generate, Ollama reads this article and crafts 5 comprehension questions. Your answers are graded against the article content — general knowledge won't be enough. Score 70+ to count toward your certificate.
Questions are cached — you'll always get the same 5 for this article.